Synthetic hormone prednisone refers to glucocorticoids. It doesn’t promote the accumulation of water and sodium in the body and doesn’t accelerate the excretion of potassium, unlike other hormone drugs.
Prednisone in its pure form is a powder of white or yellowish color. It is entirely insoluble in water. In therapy, it is used as a strong anti-allergic and anti-inflammatory drug.
Prednisone is also famous for its anti-shock and antitoxic features.
The drug is available in several pharmaceutical forms: regular tablets, ampoules with suspension for injection, and 0.5% ointment for topical use. Any of these forms of the drug should be used only with a doctor’s prescription.
When administered as a substitute therapy, the initial dose for adults is 5–20mg/day, maintaining a dose of 5–15mg/day. If necessary, the initial dose may be 20–100 mg/day, with the supporting dose at 5–20 mg/day. The daily dose should be reduced gradually. The initial dose for children is 1–2 mg/kg/day for 4–6 receptions; the maintaining dose is 0.3–0.6 mg/kg/day.
Prednisone has a long list of indications for use:
The drug is effective in the treatment of collagen diseases – diseases that are characterized by uncontrolled growth of connective tissues and blood vessels.
Prednisone is used for treating bronchial asthma, rheumatism, and inflammation of the joints. The drug is irreplaceable for lung or blood cancer.
The medication is used in the therapy of mononucleosis – a disease characterized by liver damage and swelling of the lymph nodes.
Prednisone is well proven in the treatment of skin diseases of the nervous, neural-allergic or other nature of occurrence.
Prednisone is prescribed for Addison’s disease when the production of hormones by the adrenal glands sharply decreases.
Hemostatic anemia, glomerulonephritis, and pancreatitis are also treated with this medication.
Prednisone normalizes the state of shock or collapse during surgical interventions when the pressure drops sharply.
It helps the organs to get accustomed to their transplantation and slows down the process of rejection.
You can take prednisone in case of eye diseases of an inflammatory nature and after surgery. It is a fast-acting remedy for allergic attacks, eliminating shock with a heart attack. It is used for cirrhosis of the liver, kidney failure, hepatitis and chemical poisoning.
In case of joint inflammation, injections are made directly into the joints. Prednisone is used for treating easy and non-serious diseases: arthritis, pathology of connective tissue, lung disease, bronchitis, hepatitis, gastrointestinal lesions and many others.
Prednisone in the form of an ointment is prescribed for neurodermatitis, eczema, urticaria and other skin diseases.
In addition to the extensive list of the use of the drug, prednisone also has contraindications. It cannot be used if the patient is previously diagnosed with:
- an allergic reaction to the components of the drug.
- endocarditis in acute form.
- ulcers of the intestine and stomach.
You cannot take prednisone during the period of gestation and breastfeeding of the baby.